a case report of neuroleptic malignant syndrome induced by clozapineis neuroleptic malignant syndrome diagnostic criteria adequately sensitive to identify diverse features of the syndrome?

neuroleptic malignant syndrome (nms) is a rare fatal medical complication that occurs as a result of dopaminergic receptor blockage in the caudate at the termination of the nigrostriatal pathways (1), and may occur at any time following consumption of dopamine antagonists. this disorder also occurs in cases of sudden discontinuation of dopamine agonists and antagonists (2,3). some studies have also reported the syndrome following tricyclic antidepressants (tcas) or specific serotonin reuptake inhibitors (ssris) use (4).